Ontology highlight
ABSTRACT:
SUBMITTER: Wand NO
PROVIDER: S-EPMC6614835 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Wand Nathaniel O NO Smith Darren A DA Wilkinson Andrew A AA Rushton Ashleigh E AE Busby Stephen J W SJW Styles Iain B IB Neely Robert K RK
Nucleic acids research 20190701 12
We report an approach for visualizing DNA sequence and using these 'DNA barcodes' to search complex mixtures of genomic material for DNA molecules of interest. We demonstrate three applications of this methodology; identifying specific molecules of interest from a dataset containing gigabasepairs of genome; identification of a bacterium from such a dataset and, finally, by locating infecting virus molecules in a background of human genomic material. As a result of the dense fluorescent labelling ...[more]