Prevalence of noroviruses in children hospitalized for acute gastroenteritis in Hohhot, China, 2012-2017.

ABSTRACT:

Background

Noroviruses (NVs) are an important cause of acute gastroenteritis (AGE) worldwide. There are limited data on the prevalence and molecular characterization of NVs in children in Hohhot, China.

Methods

Between January 2012 and December 2017, 1863 stool samples were collected at Maternal and Child Health Hospital in Hohhot. All samples were screened for NVs by real-time reverse transcription polymerase chain reaction (real-time RT-PCR).

Results

NVs were detected in 24.15% of these inpatient cases, ranging from 12.78 to 32.92% in different years. NV was detected throughout the year, with a peak in winter. Based on sequence analysis of the partial VP1 gene, the 306 identified NV strains were divided into six genotypes: GII.3 (71.24%), GII.4 (23.53%), and GII.2,

SUBMITTER: Li HY 

PROVIDER: S-EPMC6615110 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature