Stress and the medial temporal lobe at rest: Functional connectivity is associated with both memory and cortisol.

ABSTRACT: When acute stress is experienced immediately after memory encoding (i.e., post-encoding stress) it can significantly impact subsequent memory for that event. For example, recent work has suggested that post-encoding stress occurring in a different context from encoding impairs memory. However, the neural processes underlying these effects are poorly understood. We aimed to expand this understanding by conducting an analysis of resting functional connectivity in the period following post-encoding stress that occurred in a different context than encoding, using seed regions in the medial temporal lobes known for their roles in memory. In the current study of 44 males randomized to stress (n = 23) or control (n = 21) groups, we found that stress increased cortisol, impaired recollection of ne

SUBMITTER: Shields GS 

PROVIDER: S-EPMC6615559 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature