Association of fatty liver index with risk of incident type 2 diabetes by metabolic syndrome status in an Eastern Finland male cohort: a prospective study.

ABSTRACT:

Objective

Fatty liver disease (FLD) is increasingly recognised as a predictor of cardiometabolic risk. Our objective was to examine if metabolic syndrome (MS) status affects the association of FLD with incident type 2 diabetes (T2D) in middle-aged men.

Design

Prospective epidemiological study.

Setting

University affiliated research centre in Kuopio, Eastern Finland.

Participants

Our subjects were 1792 Finnish men without diabetes at baseline in the KuopioIschaemicHeart Disease Risk Factor Study cohort.

Outcome measure

Using fatty liver index (FLI), the association of baseline FLD with incident T2D was analysed in multivariable-adjusted Cox regression models, considering their MS statuses. The main models were adjusted for constitutional factors, lifestyl

SUBMITTER: Olubamwo OO 

PROVIDER: S-EPMC6615775 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature