Molecular epidemiological study of enterovirus D68 in hospitalised children in Hong Kong in 2014-2015 and their complete coding sequences.

ABSTRACT:

Background

Human enterovirus D68 (EV-D68) was first isolated in 1962 and has aroused public concern recently because of a nationwide outbreak among children in 2014-2015 in the USA. The symptoms include fever, runny nose, sneezing, cough and muscle pains. It might be associated with severe respiratory illness in individuals with pre-existing respiratory conditions and its potential association with acute flaccid myelitis is under investigation. In Asia, EV-D68 cases have been reported in several countries.

The study

We aimed to understand the EV-D68 prevalence and their genetic diversity in Hong Kong children.

Methods

A total of 10 695 nasopharyngeal aspirate (NPA) samples from hospitalised patients aged <18 years were collected from September 2014 to December 2015 in

SUBMITTER: Wang H 

PROVIDER: S-EPMC6615781 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature