Outcomes following early parenteral nutrition use in preterm neonates: protocol for an observational study.

ABSTRACT:

Introduction

Preterm babies are among the highest users of parenteral nutrition (PN) of any patient group, but there is wide variation in commencement, duration, and composition of PN and uncertainty around which groups will benefit from early introduction. Recent studies in critically unwell adults and children suggest that harms, specifically increased rates of nosocomial infection, outweigh the benefits of early administration of PN. In this study, we will describe early PN use in neonatal units in England, Wales and Scotland. We will also evaluate if this is associated with differences in important neonatal outcomes in neonates born between 30⁺⁰ and 32⁺⁶ weeks^+days gestation.

Methods and analysis

We will use routinely collected data from

SUBMITTER: Webbe J 

PROVIDER: S-EPMC6615825 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature