Is maternal weight gain between pregnancies associated with risk of large-for-gestational age birth? Analysis of a UK population-based cohort.

ABSTRACT:

Objective

Maternal overweight and obesity during pregnancy increases the risk of large-for-gestational age (LGA) birth and childhood obesity. We aimed to investigate the association between maternal weight change between subsequent pregnancies and risk of having a LGA birth.

Design

Population-based cohort.

Setting

Routinely collected antenatal healthcare data between January 2003 and September 2017 at University Hospital Southampton, England.

Participants

Health records of women with their first two consecutive singleton live-birth pregnancies were analysed (n=15 940).

Primary outcome measure

Risk of LGA, recurrent LGA and new LGA births in the second pregnancy.

Results

Of the 15 940 women, 16.0% lost and 47.7% gained weight (≥1 kg/m²)

SUBMITTER: Ziauddeen N 

PROVIDER: S-EPMC6615839 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature