Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications.

ABSTRACT:

Background

Studies have recently revealed that almost every type of cells including tumor cells abundantly release small vesicles known as extracellular vesicles (EVs) into the extracellular milieu. EVs carry a repertoire of biological molecules including nucleic acids, proteins, lipids, and carbohydrates and transport their cargo between cells in the vicinity as well as distantly located cells and hence act as messengers of intercellular communication. In this review, we aimed to discuss the tumor-derived exosome biology and the pivotal roles of exosomes in cancer diagnosis and treatment.

Methods

In the present review study, the authors studied several articles over the past two decades published on the kinetics of EVs in tumor environment as well as on the application of t

SUBMITTER: Rahbarghazi R 

PROVIDER: S-EPMC6617682 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature