The effect of sex and menopause on carotid intima-media thickness and pulse wave velocity in morbid obesity.

ABSTRACT:

Background

Women are relatively protected from cardiovascular disease compared with men. Since morbid obesity is an independent risk factor for cardiovascular disease, the current study investigated whether the association between sex and cardiovascular risk factors and outcomes can be demonstrated in subjects suffering from morbid obesity.

Materials and methods

Two hundred subjects enrolled in a study on cardiovascular risk factors in morbid obesity underwent extensive laboratory screening, carotid intima-media thickness (cIMT) and pulse wave velocity (PWV) measurements. Gender differences were analysed using univariate and multivariable linear regression models. In addition, the effect of menopause on cIMT and PWV was analysed. Results of these models were reported as B co

SUBMITTER: van Mil SR 

PROVIDER: S-EPMC6617718 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature