Fetal whole-heart 4D imaging using motion-corrected multi-planar real-time MRI.

ABSTRACT:

Purpose

To develop an MRI acquisition and reconstruction framework for volumetric cine visualization of the fetal heart and great vessels in the presence of maternal and fetal motion.

Methods

Four-dimensional (4D) depiction was achieved using a highly-accelerated multi-planar real-time balanced steady-state free precession acquisition combined with retrospective image-domain techniques for motion correction, cardiac synchronization and outlier rejection. The framework was validated using a numerical phantom and evaluated in a study of 20 mid- to late-gestational age human fetal subjects (23-33 weeks gestational age). Reconstructed MR data were compared with matched ultrasound. A preliminary assessment of flow-sensitive reconstruction using the velocity information encoded in

SUBMITTER: van Amerom JFP 

PROVIDER: S-EPMC6617816 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature