The role of blood pressure in risk of ischemic and hemorrhagic stroke in type 1 diabetes.

ABSTRACT:

Background

Hypertension is one of the strongest risk factors for stroke in the general population, while systolic blood pressure has been shown to independently increase the risk of stroke in type 1 diabetes. The aim of this study was to elucidate the association between different blood pressure variables and risk of stroke in type 1 diabetes, and to explore potential nonlinearity of this relationship.

Methods

We included 4105 individuals with type 1 diabetes without stroke at baseline, participating in the nationwide Finnish Diabetic Nephropathy Study. Mean age at baseline was 37.4 ± 11.9 years, median duration of diabetes 20.9 (interquartile range 11.5-30.4) years, and 52% were men. Office systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured. Base

SUBMITTER: Hagg-Holmberg S 

PROVIDER: S-EPMC6617855 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature