Analysis of ROH patterns in the Noriker horse breed reveals signatures of selection for coat color and body size.

ABSTRACT: Overlapping runs of homozygosity (ROH islands) shared by the majority of a population are hypothesized to be the result of selection around a target locus. In this study we investigated the impact of selection for coat color within the Noriker horse on autozygosity and ROH patterns. We analyzed overlapping homozygous regions (ROH islands) for gene content in fragments shared by more than 50% of horses. Long-term assortative mating of chestnut horses and the small effective population size of leopard spotted and tobiano horses resulted in higher mean genome-wide ROH coverage (S_ROH ) within the range of 237.4-284.2 Mb, whereas for bay, black and roan horses, where rotation mating is commonly applied, lower autozygosity (S_ROH from 176.4-180.0 Mb) was determined. We ident

SUBMITTER: Grilz-Seger G 

PROVIDER: S-EPMC6617995 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature