Growth in foetal life, infancy, and early childhood and the association with ocular biometry.

ABSTRACT:

Purpose

Ocular biometry varies within groups of emmetropic, hyperopic or myopic children. The aim of this study was to quantify the effect of foetal and infant growth on ocular biometry in early childhood, to determine the most important period for this association, and to examine genetic overlap with height and birth weight.

Methods

5931 children (50.1% girls) from a population-based prospective birth cohort study underwent intra-uterine and infant growth measurements at second and third trimester, and from birth to 72 months. An ophthalmic examination including axial length (mm) and corneal radius of curvature (mm) was performed at 6 years of age. The associations between prenatal and postnatal growth variables and axial length and corneal radius of curvature were assessed

SUBMITTER: Tideman JWL 

PROVIDER: S-EPMC6618159 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature