Genetic and environmental influences on the stability of psychotic experiences and negative symptoms in adolescence.

ABSTRACT:

Background

Psychotic experiences (PEs) such as paranoia and hallucinations, and negative symptoms (NS) such as anhedonia and flat affect are common in adolescence. Psychotic experiences and negative symptoms (PENS) increase risk for later psychiatric outcomes, particularly when they persist. The extent to which genetic and environmental influences contribute to the stability of PENS in mid-to-late adolescence is unknown.

Methods

Using the Specific Psychotic Experiences Questionnaire (SPEQ) twice across ~9 months in adolescence, N = 1,448 twin pairs [M = 16.32 (0.68)] reported experiences of paranoia, hallucinations, cognitive disorganization, grandiosity and anhedonia, and their parents reported on a range of NS. Individuals were split into low-scoring, decreasing, increasin

SUBMITTER: Havers L 

PROVIDER: S-EPMC6619355 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature