Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Luminal Crohn's Disease.

ABSTRACT:

Background & aims

Crohn's disease (CD) is a lifelong illness with substantial morbidity, although new therapies and treatment paradigms have been developed. We provide guidance for treatment of ambulatory patients with mild to severe active luminal CD.

Methods

We performed a systematic review to identify published studies of the management of CD. The quality of evidence and strength of recommendations were rated according to the Grading of Recommendation Assessment, Development and Evaluation (GRADE) approach. Statements were developed through an iterative online platform and then finalized and voted on by a group of specialists.

Results

The consensus includes 41 statements focused on 6 main drug classes: antibiotics, 5-aminosalicylate, corticosteroids, immunosuppress

SUBMITTER: Panaccione R 

PROVIDER: S-EPMC6619415 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature