Real-world prevalence of the inclusion criteria for the LEADER trial: Data from a national general practice network.

ABSTRACT:

Aims

To explore the prevalence and describe the clinical characteristics of people with type 2 diabetes with a similar cardiovascular (CV) profile to that of the LEADER trial participants in a primary care setting in England.

Materials and methods

In this cross-sectional analysis, using the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) network database, we identified people with type 2 diabetes meeting the LEADER inclusion criteria. We identified people's CV risk factors using computerized medical records. Additionally, we assessed the prescription pattern of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in this cohort.

Results

Of 1 275 461 adults, we identified 84 394 with type 2 diabetes, of whom 14 000 (16.6%) met the L

SUBMITTER: Hinton W 

PROVIDER: S-EPMC6619442 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature