Congenital transmission of Chagas disease in a non-endemic area, is an early diagnosis possible?

ABSTRACT:

Background

Chagas disease (CD) is an emergent disease in Europe, due to immigration. The aims of this study are to describe the epidemiological characteristics of a cohort of Chagas infected pregnant women in Spain, to assess the vertical transmission (VT) rate and evaluate the usefulness of the PCR in the diagnosis of congenital infection in the first months of life.

Methods

A descriptive, retrospective study including Chagas seropositive pregnant women who were attended at three tertiary hospitals in Madrid, from January 2012 to September 2016. Infants were examined by PCR at birth and 1 month later and serologically studied at 9 months or later. Children were considered infected when the parasite was detected by PCR at any age or when serology remained positive without de

SUBMITTER: Francisco-Gonzalez L 

PROVIDER: S-EPMC6619651 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature