Obesity is associated with increased red blood cell folate despite lower dietary intakes and serum concentrations.

ABSTRACT:

Background

Folates are essential cofactors in metabolic pathways that facilitate biological methylation and nucleotide synthesis, and therefore have widespread effects on health and diseases. Although obesity is prevalent worldwide, few studies have investigated how obesity interacts with folate status.

Objective

Based on data from the NHANES, this study aims to examine the association between body mass index (BMI) and obesity-related metabolic factors with blood folate status.

Methods

A nationally representative sample of 3767 adults from the NHANES (2003-2006) was used as the study population. Regression analyses, with and without adjustment for demographic factors and dietary intakes, were performed to examine associations between BMI and metabolic factors with ser

SUBMITTER: Bird JK 

PROVIDER: S-EPMC6619680 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature