Trial registration, publication rate and characteristics in the research field of otology: A cross-sectional study.

ABSTRACT:

Objectives

To examine 1) the publication rate of registered otology trials in ClinicalTrials.gov, 2) the public availability of the results, 3) the study characteristics associated with publication, and 4) the time to publication after trial completion.

Background

Publication bias, the publication or non-publication of research findings, depending on the nature and direction of results, is accountable for wrong treatment decisions. The extent of publication bias in otology trials has not been evaluated.

Methods

All registered otology trials were extracted from ClinicalTrials.gov with completion date up to December 2015. A search strategy was used to identify corresponding publications up to June 2017, providing at least 18 months to publish the results after trial com

SUBMITTER: van Heteren JAA 

PROVIDER: S-EPMC6619790 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature