The role of familial risk, parental psychopathology, and stress for first-onset depression during adolescence.

ABSTRACT:

Background

Adolescence represents a critical developmental period during which the initial onset of depression emerges. Family risk for depression is a salient risk factor for the initial onset of Major Depressive Disorder (MDD). We examined the effects of familial risk, stress, and behavior on the risk of developing first-onset depression.

Methods

Adolescents aged 12 to 15 with high (n = 166) or low (n = 159) familial risk for depression were assessed annually for up to five years. Stress was assessed using the Stressful Life Events Schedule and Childhood Trauma Questionnaire. The Kiddie Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version was administered to the adolescents and their parents to assess lifetime psychiatric conditions and diagnose

SUBMITTER: Elsayed NM 

PROVIDER: S-EPMC6620141 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature