Long-term observation of hepatocellular carcinoma recurrence after liver transplantation at a European transplantation centre.

ABSTRACT:

Background

The recurrence of hepatocellular carcinoma (HCC) is the strongest survival-limiting factor after liver transplantation (LT) in patients with HCC. In the face of donor organ shortage, it is necessary to identify factors associated with HCC recurrence in order to maximize the utility of the available grafts.

Objective

To study the phenomenon of HCC recurrence after LT at a European transplantation centre over the past 20 years.

Methods

Data from 304 HCC patients who underwent LT were prospectively recorded. Clinical and pathological factors were assessed for their association with recurrence.

Results

Fifty-one patients (16.8%) had HCC recurrence after LT. Patients exceeding the Milan criteria developed HCC recurrence more frequently. The time point of

SUBMITTER: Foerster F 

PROVIDER: S-EPMC6620871 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature