Serum Vitamin D and Age-Related Muscle Loss in Afro-Caribbean Men: The Importance of Age and Diabetic Status.

ABSTRACT:

Background

Prospective studies examining the potential association of vitamin D with age-related muscle loss have shown inconsistent results.

Objective

To examine the association between baseline serum 25-hydroxyvitamin D (25(OH)D), 1,25-dihydroxyvitamin D (1,25(OH)2D), and prospective change in lean mass with aging in African ancestry population. We also determined if associations were modulated by age and diabetes mellitus (DM).

Design

Prospective observational cohort study.

Setting

Data were collected from a random sub-sample of 574 men, participants of the Tobago Bone Health Study (TBHS).

Participants

574 Afro-Caribbean men, aged 43+ years (mean age: 59.1 ± 10.5), who were randomly selected as the participants in both the baseline and the follow-up v

SUBMITTER: Hwang J 

PROVIDER: S-EPMC6621556 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature