Bacterial colonization of seromas after breast cancer surgery with and without local steroid prophylaxis.

ABSTRACT:

Background

Seroma formation is a frequent postoperative sequela after mastectomy for primary breast cancer. We investigated the role of bacterial colonization of seroma fluid with three different culture methods and the effect of intracavitary steroids.

Methods

The study group consisted of 212 patients scheduled for mastectomy from a previously performed double-blind randomized placebo-controlled intervention trial. The patients were allocated to a single dose of 80 mg of steroids (methylprednisolone) or saline, and the effect on seroma formation was investigated. From each aspiration, an equal volume of seroma fluid (10 mL) was distributed into one sterile transport tube (conventional method), one aerobic blood culture bottle and one anaerobic blood culture bottle.

Resul

SUBMITTER: Axelsson CK 

PROVIDER: S-EPMC6621967 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature