Factors Associated With Excess Myocardial Infarction Risk in HIV-Infected Adults: A Systematic Review and Meta-analysis.

ABSTRACT:

Objectives

To estimate the pooled relative risk (RR) of incident acute myocardial infarction (AMI) among HIV-infected adults compared with HIV-uninfected controls and explore the contribution of traditional and HIV-related risk factors.

Background

Understanding AMI risk and associated risk factors in HIV-infected populations has the potential to inform clinical management and prevention strategies.

Methods

We systematically identified cohort studies of HIV-infected or HIV-infected and matched uninfected adults reporting AMI incidence rates published up to January 1, 2017. Random-effects meta-analysis models were used to estimate the aggregate RR of AMI by HIV status. Subgroup analysis and meta-regression were used to explore factors affecting risk.

Results

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SUBMITTER: Rao SG 

PROVIDER: S-EPMC6622459 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature