Metabolomics: population epidemiology and concordance in Australian children aged 11-12 years and their parents.

ABSTRACT:

Objectives

Nuclear magnetic resonance (NMR) metabolomics is high throughput and cost-effective, with the potential to improve the understanding of disease and risk. We examine the circulating metabolic profile by quantitative NMR metabolomics of a sample of Australian 11-12 year olds children and their parents, describe differences by age and sex, and explore the correlation of metabolites in parent-child dyads.

Design

The population-based cross-sectional Child Health CheckPoint study nested within the Longitudinal Study of Australian Children.

Setting

Blood samples collected from CheckPoint participants at assessment centres in seven Australian cities and eight regional towns; February 2015-March 2016.

Participants

1180 children and 1325 parents provided a blo

SUBMITTER: Ellul S 

PROVIDER: S-EPMC6624050 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature