SMART: Study protocol for a sequential multiple assignment randomized controlled trial to optimize weight loss management.

ABSTRACT:

Background

Stepped care is a rational resource allocation approach to reduce population obesity. Evidence is lacking to guide decisions on use of low cost treatment components such as mobile health (mHealth) tools without compromising weight loss of those needing more expensive traditional treatment components (e.g., coaching, meal replacement). A sequential multiple assignment randomization trial (SMART) will be conducted to inform the development of an empirically based stepped care intervention that incorporates mHealth and traditional treatment components.

Objective

The primary aim tests the non-inferiority of app alone, compared to app plus coaching, as first line obesity treatment, measured by weight change from baseline to 6 months. Secondary aims are to identify the

SUBMITTER: Pfammatter AF 

PROVIDER: S-EPMC6624080 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature