Dose Effects of Orally Administered Spirulina Suspension on Colonic Microbiota in Healthy Mice.

ABSTRACT: Oral supplemented nutraceuticals derived from food sources are surmised to improve the human health through interaction with the gastrointestinal bacteria. However, the lack of fundamental quality control and authoritative consensus (e.g., formulation, route of administration, dose, and dosage regimen) of these non-medical yet bioactive compounds are one of the main practical issues resulting in inconsistent individual responsiveness and confounded clinical outcomes of consuming nutraceuticals. Herein, we studied the dose effects of widely used food supplement, microalgae spirulina (Arthrospira platensis), on the colonic microbiota and physiological responses in healthy male Balb/c mice. Based on the analysis of 16s rDNA sequencing, compared to the saline-treated group

SUBMITTER: Hu J 

PROVIDER: S-EPMC6624478 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature