Spread and clinical severity of respiratory syncytial virus A genotype ON1 in Germany, 2011-2017.

ABSTRACT:

Background

The Respiratory Syncytial Virus (RSV) A genotype ON1, which was first detected in Ontario (Canada) in 2010/11, appeared in Germany in 2011/12. Preliminary observations suggested a higher clinical severity in children infected with this new genotype. We investigated spread and disease severity of RSV-A ON1 in pediatric in- and outpatient settings.

Methods

During 2010/11 to 2016/17, clinical characteristics and respiratory samples from children with acute respiratory tract infections (RTI) were obtained from ongoing surveillance studies in 33 pediatric practices (PP), one pediatric hospital ward (PW) and 23 pediatric intensive care units (PICU) in Germany. RSV was detected in the respiratory samples by PCR; genotypes were identified by sequencing. Within each settin

SUBMITTER: Streng A 

PROVIDER: S-EPMC6624929 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature