Bloodstream infections caused by multidrug-resistant gram-negative bacteria: epidemiological, clinical and microbiological features.

ABSTRACT:

Background

Bloodstream infections (BSI) are associated with high morbidity and mortality. This scenario worsens with the emergence of drug-resistant pathogens, resulting in infections which are difficult to treat or even untreatable with conventional antimicrobials. The aim of this study is to describe the epidemiological aspects of BSI caused by multiresistant gram-negative bacilli (MDR-GNB).

Methods

We conducted a laboratory-based surveillance for gram-negative bacteremia over a 1-year period. The bacterial isolates were identified by MALDI-TOF/MS and the antimicrobial susceptibility testing was performed by VITEK®2. Resistance genes were identified through PCR assays.

Results

Of the 143 patients, 28.7% had infections caused by MDR-GNB. The risk factors for MDR bact

SUBMITTER: Leal HF 

PROVIDER: S-EPMC6624930 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature