Sexual dimorphism in the incidence of human cancers.

ABSTRACT:

Background

Sex differences in the incidences of cancers become a critical issue in both cancer research and the development of precision medicine. However, details in these differences have not been well reported. We provide a comprehensive analysis of sexual dimorphism in human cancers.

Methods

We analyzed four sets of cancer incidence data from the SEER (USA, 1975-2015), from the Cancer Registry at Mayo Clinic (1970-2015), from Sweden (1970-2015), and from the World Cancer Report in 2012.

Results

We found that all human cancers had statistically significant sexual dimorphism with male dominance in the United States and mostly significant in the Mayo Clinic, Sweden, and the world data, except for thyroid cancer, which is female-dominant.

Conclusions

Sexual dim

SUBMITTER: Zheng D 

PROVIDER: S-EPMC6625025 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature