Dose variability of supplemental oxygen therapy with open patient interfaces based on in vitro measurements using a physiologically realistic upper airway model.

ABSTRACT:

Background

Supplemental oxygen therapy is widely used in hospitals and in the home for chronic care. However, there are several fundamental problems with the application of this therapy such that patients are often exposed to arterial oxygen concentrations outside of the intended target range. This paper reports volume-averaged tracheal oxygen concentration measurements (FtO2) from in vitro experiments conducted using a physiologically realistic upper airway model. The goal is to provide data to inform a detailed discussion of the delivered oxygen dose.

Methods

A baseline FtO2 dataset using a standard, straight adult nasal cannula was established by varying tidal volume (V_t), breathing frequency (f), and continuous oxygen flow rate (Q_O2) between the fol

SUBMITTER: Katz I 

PROVIDER: S-EPMC6625031 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature