Near-infrared intraoperative imaging for minimally invasive pulmonary metastasectomy for sarcomas.

ABSTRACT:

Background

Complete pulmonary metastasectomy for sarcoma metastases provides patients an opportunity for long-term survival and possible cure. Intraoperative localization of preoperatively identified metastases and identification of occult lesions can be challenging. In this trial, we evaluated the efficacy of near-infrared (NIR) intraoperative imaging using second window indocyanine green during metastasectomy to identify known metastases and to detect occult nodules.

Methods

Thirty patients with pulmonary nodules suspicious for sarcoma metastases were enrolled in an open-label, feasibility study (NCT02280954). All patients received intravenous indocyanine green (5 mg/kg) 24 hours before metastasectomy. Patients 1 through 10 (cohort 1) underwent metastasectomy via thoracoto

SUBMITTER: Predina JD 

PROVIDER: S-EPMC6625353 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature