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Designing noninferiority tuberculosis treatment trials: Identifying practical advantages for drug regimens with acceptable effectiveness.


ABSTRACT: In this Collection Review for the Novel Treatments for Tuberculosis Collection, Piero Olliaro and Michael Vaillant discuss the considerations when choosing a non-inferiority margin that is meaningful from statistical, ethical, clinical, and health standpoint.

SUBMITTER: Olliaro PL 

PROVIDER: S-EPMC6625704 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature