Retinal microvascular features and cognitive change in the Lothian-Birth Cohort 1936.

ABSTRACT:

Introduction

We test whether measures of the retinal vasculature are associated with cognitive functioning and cognitive change.

Methods

Retinal images from a narrow-age cohort were analyzed using Vessel Assessment and Measurement Platform for Images of the Retina, producing a comprehensive range of quantitative measurements of the retinal vasculature, at mean age 72.5 years (SD = 0.7). Cognitive ability and change were measured using a battery of multiple measures of memory, visuospatial, processing speed, and crystallized cognitive abilities at mean ages 73, 76, and 79 years. We applied multivariate growth curve models to test the association between retinal vascular measurements with cognitive abilities and their changes.

Results

Almost all associations were nonsig

SUBMITTER: McGrory S 

PROVIDER: S-EPMC6625967 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature