Treatment outcomes of drug-resistant tuberculosis in the Netherlands, 2005-2015.

ABSTRACT:

Background

Since in low incidence TB countries population migration and complex treatment of drug-resistant tuberculosis (DR-TB) patients are major issues, we aimed to analyse patient risk factors associated with the incidence of poor outcome of TB treatment among DR-TB patients in the Netherlands.

Methods

This retrospective cohort study included adult patients with confirmed DR-TB treated from 2005 to 2015. We obtained data from a nationwide exhaustive registry of tuberculosis patients in the Netherlands. Predictors for unsuccessful TB treatment (defaulted and failed treatment) and TB-associated mortality were analysed using multivariate logistic regression.

Results

Among 10,303 registered TB patients, 545 patients with DR-TB were analysed. Six types of DR-TB were id

SUBMITTER: Pradipta IS 

PROVIDER: S-EPMC6626402 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature