The association between tuberculin skin test result and active tuberculosis risk of college students in Beijing, China: a retrospective cohort study.

ABSTRACT:

Background

About 10% latent tuberculosis infections (LTBI) would progress to active tuberculosis (TB), if left prophylactic therapy. Tuberculin skin test (TST) is the most widely used method for LTBI screening in the school of China. However, for college students, the association between TST reaction size and active TB risk was unclear.

Methods

We conducted a retrospective study to assess whether the TST reaction size would predict active TB during the next two years after TST screening for college students. Multivariable Cox regression was performed to identify the size of TST reaction and other factors associated with active TB risk.

Results

A total of 67292 college students in Beijing, China were included in this study; 8021 (11.92%) individuals were TST positive (

SUBMITTER: Cao D 

PROVIDER: S-EPMC6626405 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature