Sociodemographic variation in the oral microbiome.

ABSTRACT:

Purpose

Variations in the oral microbiome are potentially implicated in social inequalities in oral disease, cancers, and metabolic disease. We describe sociodemographic variation of oral microbiomes in a diverse sample.

Methods

We performed 16S rRNA sequencing on mouthwash specimens in a subsample (n = 282) of the 2013-2014 population-based New York City Health and Nutrition Examination Study. We examined differential abundance of 216 operational taxonomic units, and alpha and beta diversity by age, sex, income, education, nativity, and race/ethnicity. For comparison, we examined differential abundance by diet, smoking status, and oral health behaviors.

Results

Sixty-nine operational taxonomic units were differentially abundant by any sociodemographic variable (false

SUBMITTER: Renson A 

PROVIDER: S-EPMC6626698 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature