Structures and Bioactivities of Six New Triterpene Glycosides, Psolusosides E, F, G, H, H₁, and I and the Corrected Structure of Psolusoside B from the Sea Cucumber Psolus fabricii.

ABSTRACT: Seven sulfated triterpene glycosides, psolusosides B (1), E (2), F (3), G (4), H (5), H₁ (6), and I (7), along with earlier known psolusoside A and colochiroside D have been isolated from the sea cucumber Psolus fabricii collected in the Sea of Okhotsk. Herein, the structure of psolusoside B (1), elucidated by us in 1989 as a monosulfated tetraoside, has been revised with application of modern NMR and particularly MS data and proved to be a disulfated tetraoside. The structures of other glycosides were elucidated by 2D NMR spectroscopy and HR-ESI mass-spectrometry. Psolusosides E (2), F (3), and G (4) contain holostane aglycones identical to each other and differ in their sugar compositions and t

SUBMITTER: Silchenko AS 

PROVIDER: S-EPMC6627558 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature