Mining Featured Biomarkers Linked with Epithelial Ovarian CancerBased on Bioinformatics.

ABSTRACT: : Epithelial ovarian cancer (EOC) is the18th most common cancer worldwide and the 8th most common in women. The aim of this study was to diagnose the potential importance of, as well as novel genes linked with, EOC and to provide valid biological information for further research. The gene expression profiles of E-MTAB-3706 which contained four high-grade ovarian epithelial cancer samples, four normal fallopian tube samples and four normal ovarian epithelium samples were downloaded from the ArrayExpress database. Pathway enrichment and Gene Ontology (GO) enrichment analysis of differentially expressed genes (DEGs) were performed, and protein-protein interaction (PPI) network, microRNA-target gene regulatory network and TFs (transcription factors ) -target gene regulatory network for

SUBMITTER: Alur VC 

PROVIDER: S-EPMC6628368 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature