The bread wheat epigenomic map reveals distinct chromatin architectural and evolutionary features of functional genetic elements.

ABSTRACT:

Background

Bread wheat is an allohexaploid species with a 16-Gb genome that has large intergenic regions, which presents a big challenge for pinpointing regulatory elements and further revealing the transcriptional regulatory mechanisms. Chromatin profiling to characterize the combinatorial patterns of chromatin signatures is a powerful means to detect functional elements and clarify regulatory activities in human studies.

Results

In the present study, through comprehensive analyses of the open chromatin, DNA methylome, seven major chromatin marks, and transcriptomic data generated for seedlings of allohexaploid wheat, we detected distinct chromatin architectural features surrounding various functional elements, including genes, promoters, enhancer-like elements, and transpo

SUBMITTER: Li Z 

PROVIDER: S-EPMC6628505 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature