Methylphenidate increases willingness to perform effort in adults with ADHD.

ABSTRACT:

Background

A reduced willingness to perform effort based on the magnitude and probability of potential rewards has been associated with diminished dopamine function and may be relevant to attention-deficit/hyperactivity disorder (ADHD). Here, we investigated the influence of ADHD status and methylphenidate on effort-based decisions. We hypothesized that ADHD participants would make fewer high-effort selections than non-ADHD subjects, and that methylphenidate would increase the number of high-effort selections. Furthermore, we hypothesized there would be associations among ADHD severity and methylphenidate-related changes in effort-based and attentional performance across all participants.

Methods and participants

ADHD (n = 23) and non-ADHD (n = 23) adults completed the Effor

SUBMITTER: Addicott MA 

PROVIDER: S-EPMC6628703 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature