Ontology highlight
ABSTRACT:
SUBMITTER: Orzabal MR
PROVIDER: S-EPMC6628922 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Reproductive toxicology (Elmsford, N.Y.) 20190509
Binge alcohol exposure during pregnancy results in diminished vessel function and altered proteome in the maternal uterine artery. We aimed to utilize high throughput RNA-seq deep-sequencing to characterize specific effects of binge alcohol exposure during pregnancy on the uterine artery transcriptome, and gain insight into mechanisms underlying alcohol-mediated uterine artery dysfunction. Pregnant Sprague-Dawley rats assigned to Pair-Fed Control or Alcohol groups, received a once-daily orogastr ...[more]