Role of maternal serum interleukin 17 in preeclampsia: diagnosis and prognosis.

ABSTRACT:

Background

Immunological factors play a unique role in the setting of preeclampsia; there is a rising debate about the performance of interleukin 17 (IL-17) as inflammatory mediator in its pathogenesis. The purpose of this paper was to evaluate the significance of IL-17 in the diagnosis and prognosis of preeclampsia and estimate a cutoff value for better prediction.

Methods

A prospective case control study, 40 patient were enrolled in the study, two groups were designed: a normotensive (control) group (n=20) and preeclampsia group (n=20). Both groups were compared regarding serum IL-17 level to clarify its significance, then ROC curve analysis was done to establish the best cutoff level to predict preeclampsia, with further assessment of its relation to blood pressure to det

SUBMITTER: El Shahaway AA 

PROVIDER: S-EPMC6628960 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature