Implications of insular cortex laterality for treatment of nicotine addiction.

ABSTRACT:

Background

Damage to the insula disrupts nicotine-induced cravings and is associated with greater odds of cessation. The role of laterality in regulating these changes is unclear. Neuroimaging studies in cigarette smokers show left hemispheric activation during a period of forced withdrawal and right hemispheric activation after having just smoked. Among current smokers hospitalized for stroke involving their insula, we compared left versus right insular damage and its effect on smoking outcomes.

Methods

A total of 37 smokers hospitalized with unilateral insular strokes (14 right, 23 left) were administered questionnaires to assess urge (Questionnaire on Smoking Urges) before (retrospectively) and during hospitalization and 3 months post-stroke, withdrawal during hospitaliza

SUBMITTER: Abdolahi A 

PROVIDER: S-EPMC6629032 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature