Women's health: making cardiovascular disease real.

ABSTRACT:

Purpose of review

When patients are seen for persistent chest pain in the absence of obstructive coronary artery disease, the physician must decide if the symptoms are due to myocardial ischemia in order to guide treatment.

Recent findings

Recent findings indicate that ischemia due to coronary microvascular dysfunction (CMD) is associated with subclinical coronary atherosclerosis and an adverse prognosis. Therapeutic probe trials suggest that antiatherosclerotic and anti-ischemic therapeutic strategies may be useful. A large randomized clinical trial of high-intensity statin, maximally tolerated angiotensin-converting-enzyme inhibitor or angiotensin receptor blocker and low-dose aspirin (WARRIOR NCT#03417388) is in progress.

Summary

The diagnosis of CMD should be cons

SUBMITTER: Wei J 

PROVIDER: S-EPMC6629037 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature