Apnoeic oxygenation with nasal cannula oxygen at different flow rates in anaesthetised patients: a study protocol for a non-inferiority randomised controlled trial.

ABSTRACT:

Introduction

Apnoeic oxygenation using nasal high-flow oxygen delivery systems with heated and humidified oxygen has recently gained popularity in the anaesthesia community. It has been shown to allow a prolonged apnoea time of up to 65 min as CO₂ increase was far slower compared with previously reported data from CO₂ increase during apnoea. A ventilatory exchange due to the high nasal oxygen flow was proposed explaining that phenomenon. However, recent studies in children did not show any difference in CO₂ clearance comparing high-flow with low-flow oxygen. To investigate this ventilatory exchange in adults, we plan this study comparing different oxygen flow rates and the increase of CO₂ during apnoea. We hypothesise that CO₂

SUBMITTER: Theiler L 

PROVIDER: S-EPMC6629420 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature