Ontology highlight
ABSTRACT:
SUBMITTER: Chesnut M
PROVIDER: S-EPMC6629778 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Frontiers in cellular and infection microbiology 20190709
Mosquito-borne flaviviruses can cause disease in the nervous system, resulting in a significant burden of morbidity and mortality. Disease models are necessary to understand neuropathogenesis and identify potential therapeutics and vaccines. Non-human primates have been used extensively but present major challenges. Advances have also been made toward the development of humanized mouse models, but these models still do not fully represent human pathophysiology. Recent developments in stem cell t ...[more]