Manganese Deficiency Is Required for High Itaconic Acid Production From D-Xylose in Aspergillus terreus.

ABSTRACT: Itaconic acid is used as a bio-based, renewable building block in the polymer industry. It is produced by submerged fermentations of the filamentous fungus Aspergillus terreus from molasses or starch, but research over the efficient utilization of non-food, lignocellulosic plant biomass is soaring. The objective of this study was to test whether the application of two key cultivation parameters for obtaining itaconic acid from D-glucose in high yields - Mn²⁺ ion deficiency and high concentration of the carbon source - would also occur on D-xylose, the principal monomer of lignocellulose. To this end, a carbon and energy balance for itaconic acid formation was established, which is 0.83 moles/mole D-xylose. The effect of Mn²⁺ ions on itaconic acid formation was

SUBMITTER: Kollath IS 

PROVIDER: S-EPMC6629873 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature