Immunoinformatics Based Study of T Cell Epitopes in Zea m 1 Pollen Allergen.

ABSTRACT: Background and Objectives: Zea m 1 is a pollen allergen, which is present in maize, is accountable for a type I hypersensitivity reaction in all over the world. Several effective medications are available for the disorder with various side effects. Design and verification of a peptide-based vaccine is a state-of-art technology which is more cost effective than conventional drugs. Materials and Methods: Using immunoinformatic methods, the T cell epitopes from the whole structure of this allergenic protein can be predicted. Worldwide conserved region study among the other pollen allergens has been performed for T cell predicted epitopes by using a conservancy tool. This analysis will help to identify completely conserved HLA (human leukocyte antigen) binding epitopes. Lastly, molecular docki

SUBMITTER: Basu A 

PROVIDER: S-EPMC6630604 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature