A Preliminary Metagenome Analysis Based on a Combination of Protein Domains.

ABSTRACT: Metagenomic data have mainly been addressed by showing the composition of organisms based on a small part of a well-examined genomic sequence, such as ribosomal RNA genes and mitochondrial DNAs. On the contrary, whole metagenomic data obtained by the shotgun sequence method have not often been fully analyzed through a homology search because the genomic data in databases for living organisms on earth are insufficient. In order to complement the results obtained through homology-search-based methods with shotgun metagenomes data, we focused on the composition of protein domains deduced from the sequences of genomes and metagenomes, and we utilized them in characterizing genomes and metagenomes, respectively. First, we compared the relationships based on similarities in the protein domain co

SUBMITTER: Igarashi Y 

PROVIDER: S-EPMC6630717 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature